Du hast nach {search_term_string} gesucht

How does it work?

Using an augmented reality framework that allows performing tests on complex everyday tasks while directly interacting with a user's environment and thus physically activate him, we are testing three major areas:

Spatial Memory"Hide-n-seek"
- Hide 3 Augmented Reality (AR) items in real-space
- Find them back in a random order
- Avoid environmental distraction
Prospective Memory"Fire evacuation drill"
- Learn a specific order of 3 evacuation actions using AR items
- Interact with those AR items in real-space
Executive Functions ‐  Psychomotor Processing Speed“Dual -task condition / varying difficulty levels”
- Instruction to go from point A to point B in real-space (target a hidden object)
- At the same time need to tap the speaker icon at a dynamic rhythm (dual-task) for the executive functions test
- Or tap the speaker icon while discriminating between a high-pitch target) and low pitch sound for the psychomotor processing speed test

The Science

Our goal: Find very early preclinical cognitive outcomes

Clinical trials and public health intervention programs are currently hindered by the lack of very early preclinical cognitive outcome measures, which may be used to evaluate efficacy at this early stage.

Working on our goal we focused on finding specific spatial tasks, which are likely to target brain areas prone to the earliest pathologic changes.

Our findings, later verified by independent research, suggest that midlife persons with increased risk for later life dementia already show some subtle cognitive changes principally in visuospatial functions rather than the functions most commonly currently used to investigate preclinical and prodromal AD [1].

[1] Karen Ritchie et al. The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study. Alzheimer’s & Dementia 2017

More Informationclick to enlarge

Titel 1

Titel 2

Titel 3

Titel 4

Titel 5

Leadership: Medicine, Technology & Business Acumen

Ioannis Tarnanas

Chief Scientist (CSO)

PhD in Neuroscience; focus on Alzheimer’s and cognitive performance. 15 years research Dementia & Virtual Reality and previous track record in successful start-ups. Pioneered computational (functional) biomarkers for the early screening of AD as a low cost, internet delivered and non-invasive prognostic tool.

Fabian Wahle

Chief Technology (CTO)

PhD in computational biomarkers from ETH Zürich, Technology, Management & Economics, M.Sc. Artificial Intelligence, B.Sc. Knowledge Engineering, 4 years of applied AI in medical applications, international patents on physiological marker (EU, US, Asia) with Philips Research. Certified in good clinical practice.

Adrian Locher

Chief Executive (CEO)

BA from University of St. Gallen (HSG) in Business, Economics and Law. Serial entrepreneur and startup investor with focus on Artificial Intelligence. As founder and COO he scaled Switzerland's biggest multi category e-commerce player to over CHF 100M sales. He was awarded "HSG Entrepreneur of the Year 2012", "Swiss E-Commerce Champion 2015" and was ranked "40 under 40" by Swiss Bilanz magazine.

Advisors: Healthcare innovations, technology pioneers

Professor Brenda K. Wiederhold

Behavioral Health Advisor

PhD in Clinical Health Psychology; focus on development of Virtual Reality tools for the assessment and treatment of mental health disorders. 20 years success treatment patients with anxiety, stress, and phobias with virtual reality and biosensors. CEO of Interactive Media Institute, a 501c3 non-profit committed to improving access to mental healthcare services.

Dr. Mark D. Wiederhold

Medical Advisor

MD in Clinical Medicine, PhD in Anatomic and Clinical Pathology. 30 years of research focused on development of non-invasive biosensors and Virtual Reality therapy. Over 200 publications, on staff at Scripps Clinic for 15 years. Developed numerous digital technology tools to assess cognitive function in patients with TBI and PTSD.

Professor Elgar Fleisch

Strategic Advisor

Elgar Fleisch has a double appointment at ETH Zürich and University St. Gallen (HSG). At ETH, he is a full professor of information management, at HSG of technology management. His work focuses on applications, economic impacts, and infrastructures of mobile and ubiquitous computing.

Diagnosing Alzheimer’s Disease 5 years prior to it’s onset using Augmented Reality on your iPhone.

How does it work?

Spatial Memory"Hide-n-seek"

Prospective Memory"Fire evacuation drill"

Executive Functions ‐  Psychomotor Processing Speed“Dual -task condition / varying difficulty levels”

See it in Action

The Science

Our goal: Find very early preclinical cognitive outcomes

More Informationclick to enlarge